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A rat experimental model of desmopressin-induced hyponatremia, ex vivo mice model of kidney cysts, and mice orthologous model of ADPKD* were used to validate V4C232 (MQ232) efficacy in these pathologies. (*) ADPKD: Autosomal Dominant Polycystic Kidney Disease MQ232, A Snake Toxin Derivative for Treatment of Hyponatremia and Polycystic Kidney Diseases – PubMedRead More

Effectiveness of MQ232 in an orthologous ADPKD mouse model. Xiaofang Wang, Li Jiang, Kavini Nanayakkara, Jinghua Hu, Nicolas Gilles, Vicente E. Torres.Read More